reactome 5 tools

MCP server exposing 5 tools for reactome.

Endpoint

This URL is a JSON-RPC 2.0 endpoint over HTTP. Issue POST requests with a JSON-RPC body. Browsers and search crawlers land here on GET.

POST https://gateway.pipeworx.io/reactome/mcp
Content-Type: application/json

{"jsonrpc":"2.0","id":1,"method":"tools/list"}

Tools

• search — Search across all Reactome objects.
• pathway — Full pathway record by stable id (e.g. R-HSA-68886).
• participants — Entity participants of a pathway.
• pathways_for_entity — Pathways containing an entity, looked up by external resource id (e.g. UniProt accession).
• orthologous_events — Orthologous pathways/reactions in another species.

Full documentation

Code samples (curl / TypeScript / one-click client install), schemas, and the live playground are on the pack page:
https://pipeworx.io/packs/reactome/

About Pipeworx

Pipeworx is an open MCP gateway connecting AI agents to live data. pipeworx.io