gnomad 5 tools

MCP server exposing 5 tools for gnomad.

Endpoint

This URL is a JSON-RPC 2.0 endpoint over HTTP. Issue POST requests with a JSON-RPC body. Browsers and search crawlers land here on GET.

POST https://gateway.pipeworx.io/gnomad/mcp
Content-Type: application/json

{"jsonrpc":"2.0","id":1,"method":"tools/list"}

Tools

• variant — Variant by chr-pos-ref-alt (e.g. "1-55051215-G-A") or rsid.
• gene — Gene info + variants. Accepts gene symbol (e.g. "BRCA1") or Ensembl gene id.
• region — Variants in a genomic region (≤25kb recommended).
• transcript — Fetch gnomAD variant data for an Ensembl transcript (ENST…), returning transcript coordinates, gene symbol, chromosome position, and per-variant allele frequencies from exome and genome datasets.
• search — Autocomplete-style search across gnomAD genes and variants by free-text query; returns matching Ensembl gene IDs and symbols. Use to resolve partial gene names or symbols before calling gene or variant.

Full documentation

Code samples (curl / TypeScript / one-click client install), schemas, and the live playground are on the pack page:
https://pipeworx.io/packs/gnomad/

About Pipeworx

Pipeworx is an open MCP gateway connecting AI agents to live data. pipeworx.io